Homology modeling

eagle-i ID

Resource Type

Properties

1. Resource Description

   A method to construct a reasonable model of a target protein structure from its amino acid sequence with an accuracy comparable to experimental three-dimensional structure. Homology models can be constructed if the structure of the target protein or receptor is unknown but has a high sequence similarity to a protein of known structure. Homology models are very useful for structure-based drug design, fold recognition, finding potential inhibitors, predictive protein-ligand interactive simulations and more, especially when the crystallographic structure of a target protein is not available.

2. Contact

   Mottamal, Madhu, Ph.D.

3. Related Resource

   00000136-175c-ed58-a9f8-d64580000000

4. Related Resource

   00000136-175f-181d-a9f8-d64580000000

5. Service Provided by

   RCMI Molecular Structure and Modeling Core

6. Website(s)

   http://www.chemcomp.com/software.htm

7. Website(s)

   http://www.schrodinger.com/