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Biospecimen Core (LCRC)

Directors: Moroz, Krzysztof, M.D.; Zea, Arnold H., Ph.D.

Summary:

The Louisiana Cancer Research Consortium (LCRC) Tissue Procurement and Biospecimen Core Facility (TPBCF) is a part of the infrastructure to support the conduct of basic and clinical research for members of the LCRC. The goal of the repository is to support LCRC programmatic research in order to further improve our understanding of those molecular factors that contribute to cancer and that may lead to prevention, early detection, and cure.

The mission of the Biospecimen Core is to collect high quality samples of normal and diseased human material (e.g., whole blood, cellular blood components, plasma, urine, body fluids, DNA, and tumor tissue and cells) with appropriate clinical data and to make this material available to qualified researchers at Louisiana Cancer Research Consortium while ensuring the informed consent, safety, donor anonymity, and all regulatory safeguards are in place.

Affiliations:

People:

Resources:

Biological Specimens

  • Abdominal specimens ( Biological Specimen )

    - Number of unique cases: 1
    - Peripheral blood monocyte cell (PBMC) aliquots: 8
    - Serum aliquots: 5
    - Plasma aliquots: 7
    - Urine aliquots: 20

  • Adrenal specimens ( Biological Specimen )

    - Number of unique cases: 14
    - Snap frozen aliquots: 37
    - OCT embedded aliquots: 29
    - Formalin fixed aliquots: 16
    - Serum aliquots: 59
    - Plasma aliquots: 152
    - Urine aliquots: 191

  • Brain specimens ( Biological Specimen )

    - Number of unique cases: 15
    - Snap frozen aliquots: 35
    - OCT embedded aliquots: 20
    - Formalin fixed aliquots: 21
    - Peripheral blood monocyte cell (PBMC) aliquots: 28
    - Serum aliquots: 66
    - Plasma aliquots: 115
    - Urine aliquots: 218

  • Breast specimens ( Biological Specimen )

    - Number of unique cases: 77
    - Snap frozen aliquots: 233
    - OCT embedded aliquots: 183
    - Formalin fixed aliquots: 148
    - Peripheral blood monocyte cell (PBMC) aliquots: 211
    - Serum aliquots: 315
    - Plasma aliquots: 749
    - Urine aliquots: 1038

  • Cervix specimens ( Biological Specimen )

    - Number of unique cases: 5
    - Snap frozen aliquots: 9
    - OCT embedded aliquots: 9
    - Peripheral blood monocyte cell (PBMC) aliquots: 20
    - Serum aliquots: 31
    - Plasma aliquots: 62
    - Urine aliquots: 89

  • Colon specimens ( Biological Specimen )

    - Number of unique cases: 25
    - Snap frozen aliquots: 99
    - OCT embedded aliquots: 70
    - Formalin fixed aliquots: 45
    - Peripheral blood monocyte cell (PBMC) aliquots: 64
    - Serum aliquots: 116
    - Plasma aliquots: 255
    - Urine aliquots: 337

  • Duodenum specimens ( Biological Specimen )

    - Number of unique cases: 4
    - Snap frozen aliquots: 20
    - OCT embedded aliquots: 18
    - Formalin fixed aliquots: 24
    - Peripheral blood monocyte cell (PBMC) aliquots: 5
    - Serum aliquots: 19
    - Plasma aliquots: 39
    - Urine aliquots: 59

  • Endometrium specimens ( Biological Specimen )

    - Number of unique cases: 5
    - Snap frozen aliquots: 15
    - OCT embedded aliquots: 15
    - Formalin fixed aliquots: 18
    - Peripheral blood monocyte cell (PBMC) aliquots: 17
    - Serum aliquots: 15
    - Plasma aliquots: 52
    - Whole blood aliquots: 3
    - Urine aliquots: 77

  • Fat specimens ( Biological Specimen )

    - Number of unique cases: 16
    - Snap frozen aliquots: 73
    - OCT embedded aliquots: 55
    - Formalin fixed aliquots: 82
    - Peripheral blood monocyte cell (PBMC) aliquots: 30
    - Serum aliquots: 52
    - Plasma aliquots: 187
    - Urine aliquots: 224

  • Gall bladder specimens ( Biological Specimen )

    - Number of unique cases: 2
    - Peripheral blood monocyte cell (PBMC) aliquots: 13
    - Serum aliquots: 4
    - Plasma aliquots: 14
    - Urine aliquots: 38

  • Head and neck specimens ( Biological Specimen )

    - Number of unique cases: 31
    - Snap frozen aliquots: 54
    - OCT embedded aliquots: 36
    - Formalin fixed aliquots: 43
    - Peripheral blood monocyte cell (PBMC) aliquots: 139
    - Serum aliquots: 154
    - Plasma aliquots: 337
    - Urine aliquots: 357

  • Kidney specimens ( Biological Specimen )

    - Number of unique cases: 36
    - Snap frozen aliquots: 103
    - OCT embedded aliquots: 63
    - Formalin fixed aliquots: 39
    - Peripheral blood monocyte cell (PBMC) aliquots: 344
    - Serum aliquots: 154
    - Plasma aliquots: 92
    - Urine aliquots: 401

  • Kidney urine specimens ( Biological Specimen )

    - Number of unique cases: 5
    - Urine aliquots: 59

  • Larynx specimens ( Biological Specimen )

    - Number of unique cases: 15
    - Snap frozen aliquots: 20
    - OCT embedded aliquots: 18
    - Formalin fixed aliquots: 21
    - Peripheral blood monocyte cell (PBMC) aliquots: 38
    - Serum aliquots: 63
    - Plasma aliquots: 154
    - Urine aliquots: 100

  • Leukemia specimens ( Biological Specimen )

    - Number of unique cases: 12
    - Peripheral blood monocyte cell (PBMC) aliquots: 109
    - Serum aliquots: 35
    - Plasma aliquots: 190
    - Urine aliquots: 61

  • Liver specimens ( Biological Specimen )

    - Number of unique cases: 19
    - Snap frozen aliquots: 63
    - OCT embedded aliquots: 42
    - Formalin fixed aliquots: 95
    - Peripheral blood monocyte cell (PBMC) aliquots: 54
    - Serum aliquots: 101
    - Plasma aliquots: 248
    - Urine aliquots: 266

  • Lung specimens ( Biological Specimen )

    - Number of unique cases: 1
    - Snap frozen aliquots: 8
    - OCT embedded aliquots: 4
    - Formalin fixed aliquots: 4
    - Peripheral blood monocyte cell (PBMC) aliquots: 5
    - Serum aliquots: 7
    - Plasma aliquots: 16
    - Urine aliquots: 20

  • Lymph node specimens ( Biological Specimen )

    - Number of unique cases: 7
    - Snap frozen aliquots: 17
    - OCT embedded aliquots: 15
    - Formalin fixed aliquots: 9
    - Peripheral blood monocyte cell (PBMC) aliquots: 23
    - Serum aliquots: 28
    - Plasma aliquots: 54
    - Whole blood aliquots: 8
    - Urine aliquots: 79

  • Mandible specimens ( Biological Specimen )

    - Number of unique cases: 2
    - Snap frozen aliquots: 7
    - OCT embedded aliquots: 3
    - Peripheral blood monocyte cell (PBMC) aliquots: 9
    - Serum aliquots: 12
    - Plasma aliquots: 22
    - Urine aliquots: 38

  • Muscle specimens ( Biological Specimen )

    - Number of unique cases: 2
    - Snap frozen aliquots: 8
    - OCT embedded aliquots: 8
    - Formalin fixed aliquots: 12
    - Peripheral blood monocyte cell (PBMC) aliquots: 19
    - Serum aliquots: 15
    - Plasma aliquots: 42
    - Urine aliquots: 40

  • Omentum specimens ( Biological Specimen )

    - Number of unique cases: 5
    - Snap frozen aliquots: 15
    - OCT embedded aliquots: 10
    - Formalin fixed aliquots: 30
    - Peripheral blood monocyte cell (PBMC) aliquots: 4
    - Serum aliquots: 16
    - Plasma aliquots: 44
    - Urine aliquots: 78

  • Ovary specimens ( Biological Specimen )

    - Number of unique cases: 16
    - Snap frozen aliquots: 73
    - OCT embedded aliquots: 43
    - Formalin fixed aliquots: 55
    - Peripheral blood monocyte cell (PBMC) aliquots: 56
    - Serum aliquots: 77
    - Plasma aliquots: 202
    - Whole blood aliquots: 8
    - Urine aliquots: 244

  • Palate specimens ( Biological Specimen )

    - Number of unique cases: 3
    - Snap frozen aliquots: 6
    - OCT embedded aliquots: 4
    - Formalin fixed aliquots: 3
    - Peripheral blood monocyte cell (PBMC) aliquots: 1
    - Serum aliquots: 14
    - Plasma aliquots: 18

  • Pancreas specimens ( Biological Specimen )

    - Number of unique cases: 21
    - Snap frozen aliquots: 56
    - OCT embedded aliquots: 42
    - Formalin fixed aliquots: 29
    - Peripheral blood monocyte cell (PBMC) aliquots: 68
    - Serum aliquots: 100
    - Plasma aliquots: 233
    - Urine aliquots: 392

  • Parotid specimens ( Biological Specimen )

    - Number of unique cases: 2
    - Snap frozen aliquots: 2
    - OCT embedded aliquots: 1
    - Peripheral blood monocyte cell (PBMC) aliquots: 7
    - Serum aliquots: 13
    - Plasma aliquots: 27
    - Urine aliquots: 40

  • Peritoneum specimens ( Biological Specimen )

    - Number of unique cases: 2
    - Snap frozen aliquots: 1
    - OCT embedded aliquots: 1
    - Peripheral blood monocyte cell (PBMC) aliquots: 3
    - Serum aliquots: 9
    - Plasma aliquots: 21
    - Urine aliquots: 30

  • Pharynx specimens ( Biological Specimen )

    - Number of unique cases: 1
    - Peripheral blood monocyte cell (PBMC) aliquots: 5
    - Serum aliquots: 8
    - Plasma aliquots: 13
    - Urine aliquots: 20

  • Prostate blood specimens ( Biological Specimen )

    - Number of unique cases: 150
    - Peripheral blood monocyte cell (PBMC) aliquots: 19
    - Serum aliquots: 658
    - Plasma aliquots: 530
    - Whole blood aliquots: 503

  • Prostate specimens ( Biological Specimen )

    - Number of unique cases: 239
    - Snap frozen aliquots: 609
    - Formalin fixed aliquots: 887
    - Peripheral blood monocyte cell (PBMC) aliquots: 804
    - Serum aliquots: 1094
    - Plasma aliquots: 2075
    - Whole blood: 8
    - Urine aliquots: 3508

  • Rectum specimens ( Biological Specimen )

    - Number of unique cases: 3
    - Peripheral blood monocyte cell (PBMC) aliquots: 6
    - Serum aliquots: 4
    - Plasma aliquots: 22
    - Urine aliquots: 37

  • Scalp specimens ( Biological Specimen )

    - Number of unique cases: 2
    - Snap frozen aliquots: 3
    - OCT embedded aliquots: 3
    - Peripheral blood monocyte cell (PBMC) aliquots: 4
    - Serum aliquots: 12
    - Plasma aliquots: 26
    - Urine aliquots: 19

  • Skin specimens ( Biological Specimen )

    - Number of unique cases: 18
    - Snap frozen aliquots: 52
    - OCT embedded aliquots: 35
    - Formalin fixed aliquots: 44
    - Peripheral blood monocyte cell (PBMC) aliquots: 54
    - Serum aliquots: 78
    - Plasma aliquots: 189
    - Whole blood aliquots: 4
    - Urine aliquots: 217

  • Small intestine specimens ( Biological Specimen )

    - Number of unique cases: 3
    - Snap frozen aliquots: 14
    - OCT embedded aliquots: 14
    - Formalin fixed aliquots: 23
    - Peripheral blood monocyte cell (PBMC) aliquots: 11
    - Serum aliquots: 16
    - Plasma aliquots: 45
    - Urine aliquots: 59

  • Spleen specimens ( Biological Specimen )

    - Number of unique cases: 4
    - Snap frozen aliquots: 17
    - OCT embedded aliquots: 10
    - Formalin fixed aliquots: 13
    - Peripheral blood monocyte cell (PBMC) aliquots: 10
    - Serum aliquots: 9
    - Plasma aliquots: 33
    - Whole blood aliquots: 4
    - Urine aliquots: 52

  • Stomach specimens ( Biological Specimen )

    - Number of unique cases: 2
    - Snap frozen aliquots: 17
    - OCT embedded aliquots: 6
    - Formalin fixed aliquots: 1
    - Peripheral blood monocyte cell (PBMC) aliquots: 15
    - Serum aliquots: 9
    - Plasma aliquots: 30
    - Urine aliquots: 40

  • Superglottis specimens ( Biological Specimen )

    - Number of unique cases: 1
    - Snap frozen aliquots: 1
    - OCT embedded aliquots: 2
    - Formalin fixed aliquots: 1
    - Peripheral blood monocyte cell (PBMC) aliquots: 3
    - Serum aliquots: 6
    - Plasma aliquots: 7

  • Thyroid specimens ( Biological Specimen )

    - Number of unique cases: 86
    - Snap frozen aliquots: 139
    - OCT embedded aliquots: 98
    - Formalin fixed aliquots: 33
    - Peripheral blood monocyte cell (PBMC) aliquots: 201
    - Serum aliquots: 348
    - Plasma aliquots: 731
    - Whole blood aliquots: 8
    - Urine aliquots: 1122

  • Tonsil specimens ( Biological Specimen )

    - Number of unique cases: 2
    - Snap frozen aliquots: 10
    - OCT embedded aliquots: 6
    - Formalin fixed aliquots: 2
    - Peripheral blood monocyte cell (PBMC) aliquots: 5
    - Serum aliquots: 2
    - Plasma aliquots: 5

  • Trachea specimens ( Biological Specimen )

    - Number of unique cases: 2
    - Formalin fixed aliquots: 4
    - Peripheral blood monocyte cell (PBMC) aliquots: 4
    - Serum aliquots: 6
    - Plasma aliquots: 13
    - Urine aliquots: 20

  • Uterus specimens ( Biological Specimen )

    - Number of unique cases: 11
    - Snap frozen aliquots: 38
    - OCT embedded aliquots: 21
    - Formalin fixed aliquots: 11
    - Peripheral blood monocyte cell (PBMC) aliquots: 31
    - Serum aliquots: 46
    - Plasma aliquots: 116
    - Urine aliquots: 181

  • Vaginal specimens ( Biological Specimen )

    - Number of unique cases: 2
    - Snap frozen aliquots: 8
    - OCT embedded aliquots: 6
    - Peripheral blood monocyte cell (PBMC) aliquots: 5
    - Serum aliquots: 10
    - Plasma aliquots: 19
    - Urine aliquots: 20

  • Vocal chord specimens ( Biological Specimen )

    - Number of unique cases: 3
    - Snap frozen aliquots: 3
    - OCT embedded aliquots: 3
    - Peripheral blood monocyte cell (PBMC) aliquots: 17
    - Serum aliquots: 16
    - Plasma aliquots: 37
    - Urine aliquots: 39

Instruments

  • Cryostat ( Cryostat )

    "The cryostat is used for sectioning frozen tissues at sub-zero temperatures for further analysis."

  • Thermo CryoPlus Series Liquid Nitrogen Storage System ( Environmental control system )

    "The CryoPlus Liquid Nitrogen Storage system has a storage capacity of 13,000 vials (2.0 ml) and features a vacuum insulated storage tank with stainless steel interior. The counterbalanced lid with 100% clearance incorporates high density, foamed-in-place urethane insulation with dedicated vent (patent pending). Two independent flexible gaskets reduce the migration of moisture into the chamber to reduce icing. For maximum product security, both series provide front-mounted key lock, rear mounted, recessed power switch and re mote alarm contacts. Both series are UL listed, CSA Certified, bear the CE mark and meet the requirements IEC 1010."

Services

  • Biospecimen storage ( Material storage service )

    "Samples can be stored in the liquid nitrogen storage system for a fee for investigators choosing to do so. Biospecimens collected for specific studies will be kept in distinctly identified locations so as to keep them separate from the general TB."

  • Blood procurement ( Support service )

    "This includes general procurement of blood and plasma samples from patients bearing tumors and from normal controls."

  • Quality assurance/histopathologic review ( Material analysis service )

    "Histopathologic verification of collected tissue samples will be performed in the Histopathology Laboratory of the Department of Pathology at Tulane University School of Medicine. Dr. Moroz will verify each collected sample for their representation of a pathologic process. The use of clinical histology lab assures the highest standard in tissue processing and compliance with federal and state regulations (CAP, CLIA). Representative histologic and gross images of collected samples (tumoral and non-tumoral) will be digitized. A secure web link to the LCRC Biospecimen Database will allow researchers to view the availability and quality of research samples for use."

  • Tissue procurement ( Support service )

    "This includes general procurement and specific investigator-directed procurement of fresh frozen, formalin-fixed paraffin embedded malignant and non-malignant tissue (including tumor tissue and adjacent or distant non-tumor tissue from the same surgery)."


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Last updated: 2015-09-21T10:55:14.970-05:00

Copyright © 2016 by the President and Fellows of Harvard College
The eagle-i Consortium is supported by NIH Grant #5U24RR029825-02 / Copyright 2016