This is a summary list of all core laboratories at Xavier University of Louisiana . The list includes links to more detailed information, which may also be found using the eagle-i search app.
Core purpose: "To propagate, expand and supply high quality samples of normal mesenchymal stem cells (MSCs) from in vitro cultures with appropriate quality control assurances for use by LCRC investigators who are studying any aspect of MSCs in relationship to cancer."
To provide the best husbandry and environment for housing, maintaining, and caring for research and laboratory animals used at Xavier University, with in all applicable guidelines, and to assist users by providing information and support for handling and care of animals.
The Louisiana Cancer Research Consortium (LCRC) Tissue Procurement and Biospecimen Core Facility (TPBCF) is a part of the infrastructure to support the conduct of basic and clinical research for members of the LCRC. The goal of the repository is to support LCRC programmatic research in order to further improve our understanding of those molecular factors that contribute to cancer and that may lead to prevention, early detection, and cure.
The mission of the Biospecimen Core is to collect high quality samples of normal and diseased human material (e.g., whole blood, cellular blood components, plasma, urine, body fluids, DNA, and tumor tissue and cells) with appropriate clinical data and to make this material available to qualified researchers at Louisiana Cancer Research Consortium while ensuring the informed consent, safety, donor anonymity, and all regulatory safeguards are in place.
The Cell Analysis & Immunology Core Facility is a customer oriented service dedicated to supporting the research needs of the investigators of the Louisiana Cancer Research Consortium (LCRC). It provides state-of-art instrumentation and expertise for addressing experimental issues related to single cells, nuclei and chromosomes.
In addition to instrumentation, the Facility intends to collaborate with the investigators and contribute to all aspects of the research process. This includes consultation in experimental design, technical assistance in the operation of instruments, trouble shooting, data analysis and storage, interpretation of results and preparation and production of presentation graphics. The Facility is also communicating with investigators in other institutions and is devoted to introducing and developing new applications on our flow cytometers. In this way, investigators are provided with unlimited possibilities to answer questions regarding nature and function of cells by flow cytometry.
The center is focused on understanding and overcoming barriers to efficient oral, colonic, parenteral, pulmonary and vaginal delivery of drugs in the hopes of developing new treatments for chronic diseases such as cancer. Numerous new technologies are coming out of the Center as relationships have been formed with small, advanced technology businesses.
The Genomics Core Facility is a core resource of LSU Health Science Center, sponsored jointly by the Cancer Center and Genetics Center. The Facility is committed to providing quality service by fulfilling the needs of the research community in a consistently rapid, dependable, and economical fashion. Services include automated DNA sequencing, using state-of-the-art instrumentation (ABI PRISM 3130XL Genetic Analyzers) and the latest protocols to ensure high quality results at reseasonable prices. The Facility also houses an ABI Prism 7900 HT (a high through-put real-time PCR system) and a Biomek2000 liquid handling robot.
The Major Instrumentation Core has been established to provide technical services and consumable supplies necessary for the operation and maintenance of a variety of major instruments that support biomedical research at Xavier University. The long term goal of the Major Instrumentation Core is to enhance the overall biomedical research capabilities at Xavier University by making available essential instrument-based platforms for various research projects. To achieve this goal the Major Instrumentation Core has set the following specific aims:
1). support biomedical research projects on campus by providing essential analytical instrumentation,
2). maintain and operate existing instruments,
3). acquire new instruments, and
4). provide technical support for user community of the core.
Shared instrumentation facilities across Xavier University's research community
In December 2000, the LSUHSC Program in Gene Therapy in conjunction with the Louisiana Gene Therapy Research Consortium created the Microarray Core to cater to the growing needs of investigators who wanted to perform expression studies. Since that time, our core has helped researchers from around the world process over 3000 samples, resulting in numerous peer-reviewed scientific publications.
The purpose of this core laboratory is to assist investigators requiring detection, imaging, and morphometric analysis of gene and protein expression in any type of cell and tissue. Services, expertise and state-of -the-art biomedical imaging services will be provided with the hope of broadening and streamlining all morphological research.
The mission of Proteomics Core Facility is to help researchers advance their biomedical research programs. The Facility is equipped with gel electrophoresis units, image analyzers and digitizers, and robotics for mass spectrometry sample preparation. Currently, a Matrix-Assisted Laser Desorption/Ionization Mass Spectrometer instrument implements protein identification. The various applications include the studies of protein expression profile, posttranslational modifications, and partial sequencing of novel proteins. The staff also consult with researchers about their particular research interests and assist with the development of specific applications and solution to problems.
The RCMI Cell and Molecular Biology Core (CMB Core) provides focused services using cell and molecular biological techniques. It also provides access, upkeep and training on “state of the art” equipment. Funding by the RMCI allows these services to be offered at minimal cost to users of the core. Technical services and necessary consumable supplies are provided to support cancer research projects at Xavier University. The long term goal of the Cell and Molecular Biology Core is to enhance the overall biomedical research capabilities at Xavier University.
A Molecular Structure and Modeling Core laboratory has been established to provide technical services to support faculty researchers involved in cancer research and drug design at Xavier University. Drug design methods use molecular structure information and modeling methods to determine structure patterns among active and inactive compounds, identify and compare potential active sites, and screen databases to identify new leads. X-ray crystallography provides structure coordinates for druglike, organic compounds and small peptides. The goal of this core laboratory is to provide small molecule X-ray crystallographic services as well as to support ligand-based and structure-based drug design projects at any stage. The long term goal is to develop resources in order to enhance cancer related biomedical research capability at Xavier University. To achieve this goal, the Molecular Structure and Modeling Core Laboratory has set the following specific aims:
1. To provide salary support for a Core Scientist to provide molecular modeling services and training in support of Xavier faculty research projects
2. To establish new collaborations with faculty at other local and RCMI institutions who might benefit from molecular modeling services
3. To provide small molecule x-ray crystallography services
4. To provide support and maintenance costs for equipment in the MSM Core
Found 13 core laboratories .